|Cordyceps Sinensis is an important medicinal fungus. Cordyceps Sinensis has broad applications in diabetes treatment. Cordyceps has demonstrated several positive effects in the treatment of diabetes and diabetes-related diseases including helping prevent blood clots, decreasing the chance of certain types of irregular heart beats, lowering blood sugar, and reduction of triglycerides and cholesterol, with all of these contributing to better microcirculation.
A polysaccharide derivative of Cordyceps was able to significantly lower plasma blood glucose, and was shown to increase the activity of a liver enzyme (glucokinase) responsible for decreasing internal sugar production and helped regulate sugar processing by the liver. A similar polysaccharide derivative from Cordyceps reduced blood glucose levels to normal in diabetic laboratory animals, increased the livers glucose-handling ability, and lowered triglyceride and cholesterol levels.
The cholesterol lowering effect of Cordyceps showed increased high-density lipoprotein (HDL) levels and decreased very low-density lipoprotein and low-density lipoprotein cholesterol levels (VLDL + LDL) in subjects that were fed cholesterol-enriched diets.
In addition to lowering cholesterol, Cordyceps was demonstrated to significantly decrease the levels of elevated free radicals in the blood that converts cholesterol to an even more damaging form. Evidence also showed a protective effect of Cordyceps to help prevent the deposit of cholesterol into the biggest blood vessel in the body, the aorta thus helping slow the development of hardening of the arteries.
Cordyceps is thus able to contribute to ones overall cardiovascular health which is essential when striving to diminish diabetic complications.
The antioxidant properties of Cordyceps on fats within the blood, such as cholesterol represent a considerable added benefit to those already mentioned for this medicine in the treatment of diabetes and heart disease. Cordyceps provide potent antioxidant protection and can help the body slow the accumulation of a substance (cholesterol ester) into the walls of arteries.
Prevention of free radical damage is an important factor in the care of diabetes; damaging processes occur at an accelerated rate in people with diabetes, and may play a major role in the long-term negative consequences of this disease.
Cordyceps should be considered one of the premier natural medicines for the treatment of diabetes and its associated disease conditions. No standard pharmaceutical medication performs such widespread actions that can be directed at lowering of blood sugar levels and preventing negative effects from diabetes lowering and protection of cholesterol levels.
Therapies aimed at protecting the heart and cardiovascular system in addition to stabilizing blood sugar are gaining recognition as a definitive treatment for diabetes and related conditions.
1 Kiho T, Ookubo K., Usui S, Hirano K. Structural features and hypoglycemic activity of a polysaccharide (CS-F10) from the cultured mycelium of Cordyceps Sinensis. Biol Pharm Bull. 1999 Sep;22 (9):966-70
2 Kiho T, Yamane A, Hui J, Usui S, Ukai S. Polysaccharide in fungi XXXVI. Hypoglycemic activity of a polysaccharide(CS-F30) from the cultural mycelium of Cordyceps Sinensis and its effect on glucose metabolism in mouse liver. Biol Pharm Bull. 1996 Feb;(2): 294-6
3 Koh JH, Kim JM, Chang UJ, Suh HJ. Hypocholesterolemic effect of hot water extract from mycelia of Cordyceps Sinensis. Biol Pharm Bull. 2003 Jan; 26(1): 84-7
4 Yamaguchi Y, Kagota S, Nakamura K, Shinozuka K, Kunitomo M. Inhibitory effects of water extracts from fruiting bodies cultured Cordyceps Sinensis on raised serum lipid peroxide levels and aortic cholesterol deposition in atherosclerotic mice. Phytother Res. 2000 Dec; 14(8): 650-2
5 Yamaguchi Y, Kagota S, Nakamura K, Shinozuka K, Kunitomo M. Antioxidant activity of the extracts from fruiting bodies of cultured Cordyceps Sinensis. Phytother Res. 2000 Dec: 14(8): 647-9
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